Thomas J. Morrow , Ph.D. ~Clinical Neurophysiologist , Neurology Svc., VA Medical Center ~Research Professor, Dept. of Neurology ~Adjunct Professor, Dept. of Molecular and Integrative Physiology Research (11R); Bldg 31 #220 2215 Fuller Rd Ann Arbor, MI  48105 ruscat@umich.edu Visit the Morrow Lab Home

Current Research:  

Research in my laboratory focuses on determining the neural mechanisms of pain and somatic sensation using behavioral, neurophysiological and brain imaging techniques in animals.  We recently developed an model for examining changes in regional cerebral blood flow (rCBF) during pain perception in animals.  Current studies have applied this imaging technique to identify key spatial and temporal relationships among forebrain structures which comprise a neural network for neuropathic pain in rats with insulin dependent diabetes mellitus (IDDM). This brain imaging approach complements other studies from our laboratory using positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) in humans.

Representative Publications:

Morrow, TJ and Casey, KL: Understanding Central Pain: New Insights from Forebrain Imaging Studies of Patients and of Animals with Central Lesions.  In: Yezierski, RP and Burchiel, KJ (Eds.) Spinal Cord Injury Pain: Assessment, Mechanisms, and Management, Vol. 23, IASP Press, Seattle, WA, 2002, pp 265-279. (SCI-Pain-2003.pdf)

Lorenz J, Cross DJ, Minoshima S, Morrow TJ, P.E. Paulson PE, and Casey KL:  A Unique Representation Of Heat Allodynia In The Human Brain. Neuron, 2002, 383-393. (neuron2002.pdf)

Paulson PE, Casey KL, Morrow TJ: .Long Term Changes in Behavior and Regional Cerebral Blood Flow Associated with Painful Peripheral Mononeuropathy in the Rat. Pain. 2002, 95:31-40. (pain-95-2002.pdf)

Morrow TJ and Casey KL: Attention-related, cross modality modulation of somatosensory neurons in primate ventrobasal (VB) thalamus. Somatosensory and Motor Research, 2000, 17 (2): 133-144. (Somatosensory-Motor_Res-17-2000.pdf)

Morrow TJ, Paulson PE, Brewer KL, Yesierski RP, K.L. Casey.  Spinal cord injury (SCI) increases forebrain regional cerebral blood flow (rCBF) in rat. Exptl Neurology, 2000, 161: 220-226.(exptl-neurol-161-2000.pdf)

Paulson PE, Morrow TJ, K.L. Casey: Bilateral behavioral and regional cerebral blood flow changes during painful peripheral mononeuropathy in the rat. PAIN, 2000, 84: 233-245. (pain84-2000.pdf)

Casey KL, Svensson P, Morrow TJ, Raz J, Jone C, Minoshima S: Selective opiate modulation of nociceptive processing in the human brain. J. Neurophysiol, 2000, 84: 525-533. (j-neurophys-84-2000.pdf)

Morrow TJ, Paulson PE, Danneman PJ, Casey, K.L.:  Regional changes in forebrain activation during the early and late phase of formalin nociception: analysis using cerebral blood flow in the rat.  PAIN, 1998, 75 (2,3): 355-365. (pain75-1998.pdf)

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