Faculty Profiles
Current Research:
Representative Publications:
Lydic R and Baghdoyan HA. "Sleep, Anesthesiology, and the Neurobiology of Arousal State Control." Anesthesiolog, 103: 1268-95, 2005.
Lydic R and Baghdoyan HA. "Sleep and Anesthesia." Foundations of Anesthesia: Basic and Clinical Sciences, 2nd Edition. Edited by H.C. Hemmings and P.M. Hopkins. 361-371, 2005.
Bernard R, Lydic R, and Baghdoyan HA. "Hypocretin Receptor-Activated G Proteins Revealed by [ 35S]GTP g S Autoradiography." The Orexin/Hypocretin System: Physiology and Pathophysiology, editors: S. Nishino and Takeshi Sakurai. 83-96, 2006 .
Bernard R, Lydic R, Baghdoyan HA. "Hypocretin (Orexin) Receptor Subtypes Differentially Enhance Acetylcholine
Lydic R and Baghdoyan HA. "Relevance of Anesthesiology for Sleep Medicine." Encyclopedia of Sleep Medicine, edited by T. Lee-Chiong. 927-932, 2006.
Lydic R, Garza-Grande R, Struthers R, Baghdoyan HA. "Nitric Oxide in B6 Mouse and Nitric Oxide-Sensitive Soluble Guanylate Cyclase in Cat Modulate Acetylcholine Release in Pontine Reticular Formation." J Appl Physiol, 100:1666-1673, 2006.
Lydic R and HA Baghdoyan. Neurochemical mechanisms mediating opioid-induced REM sleep disruption. In: Sleep and Pain, edited by G. Lavigne, M. Choiniere, B.J. Sessle, and P. Soja. Seattle : International Association for the Study of Pain, pp 99-122, 2007
Hambrecht VS, Vilsides PE, Row BW, Gozal D, Baghdoyan HA, Lydic R, Hypocia modulated cholinergic but not opiod activation of G proteins in rat hippocampus. Hippocampus, 2007; 17(10):934-42
Watson CJ, Lydic R, Baghdoyan HA. "Sleep and GABA Levels in the Oral Part of Rat Pontine Reticular Formation are Decreased by Local and Systemic Administration of Morphine." Neuroscience, 144:375-86, 2007.
Skulsky EM, Osman NI, Baghdoyan HA, Lydic R, Microdialysis delivery of morphine to the hypoglossal nucleus of Wistar rat increases hypoglosssal acetylcholine release. Sleep. 2007 May 1; 30(5);566-73
Lydic R, and H.A. Baghdoyan. Acetylcholine modulates sleep and wakefulness: A synaptic perspective. In: The Neurochemistry of Sleep and Wakefulness. Edited by J.M. Monti, S.R. Pandi-Perumal, and C.M. Sinton. Cambridge University Press, (in press) 2008
Skulsky EM, Osman NI, Baghdoyan HA, Lydic R. Microdialysis delivery of morphine to the hypoglossal nucleus of Wistar rat increases hypoglossal acetylcholine release. Sleep 30:566-573, 2007.
Hambrecht VS, Vlisides PE, Row BW, Gozal D, Baghdoyan HA, and Lydic R. Cholinergic and opioid activation of G proteins in rat hippocampus: Modulation by hypoxia. Hippocampus 17: 934-942, 2007.
Watson CJ, Soto-Calderon H, Lydic R and Baghdoyan HA. Wakefulness is increased by increasing GABA Levels in rat pontine reticular formation: A possible mechanism by which hypocretin-1 promotes arousal. Sleep 31: 453- 464, 2008.
Brummett CM, Norat MA, Palmisano JM, Lydic, R. Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block in rat. Anesthesiology (In Press) 2008.
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