Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment.
Rogers DC. Fisher EM. Brown SD. Peters J. Hunter AJ. Martin JE.
Neurobehavioral characterization of APP23 transgenic mice with the SHIRPA primary screen.
Lalonde R. Dumont M. Staufenbiel M. Strazielle C.
Spermidine/spermine N1-acetyltransferase overexpression in mice induces hypoactivity and spatial learning impairment.
Kaasinen SK, Oksman M, Alhonen L, Tanila H, Janne J
Late onset Tay–Sachs disease in mice with targeted disruption of the Hexa gene: behavioral changes and pathology of the central nervous system
Elena I. Miklyaeva, Weijia Dong, Alexandre Bureau, Roya Fattahie, Yongqin Xu, Meng Su, Gordon H. Fick, Jing-Qi Huang, Suleiman Igdoura, Nobuo Hanai and Roy A. Grave
Characterization of carbon disulfide neurotoxicity in C57BL6 mice: behavioral, morphologic, and molecular effects.
Sills RC. Valentine WM. Moser V. Graham DG. Morgan DL.
Ataxia with loss of Purkinje cells in a mouse model for Refsum disease.
Ferdinandusse S, Zomer AW, Komen JC, van den Brink CE, Thanos M, Hamers FP, Wanders RJ, van der Saag PT, Poll-The BT, Brites P
Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study.
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Mice expressing L345P mutant desmin exhibit morphological and functional changes of skeletal and cardiac mitochondria.
Kostareva A, Sjoberg G, Bruton J, Zhang SJ, Balogh J, Gudkova A, Hedberg B, Edstrom L, Westerblad H, Sejersen T
Behavioural and histopathological alterations in mice with cerebral malaria.
Lackner P, Beer R, Heussler V, Goebel G, Rudzki D, Helbok R, Tannich E, Schmutzhard E
The dark phase improves genetic discrimination for some high throughput mouse behavioral phenotyping.
Hossain SM, Wong BK, Simpson EM
Comparison of simultaneous measurement of mouse systolic arterial blood pressure by radiotelemetry and tail-cuff methods
Whitesall Steven E., Hoff Janet B., Vollmer Alan P., D'Alecy Louis G.
Characterization of heart size and blood pressure in the vitabmin D receptor knockout mouse
Robert U. Simpson, Steven H Hershey, and Karla A. Nibbelink
Prenatal exposure to nicotine modifies kidney weight and blood pressure in genetically susceptible rats: A case of gene-environment interaction
Adenka Pausova, Tomas caron Paus, Lucie S caronedova and Julie Berube
Two closely linked interactive blood pressure QTL on rat chromosome 5 defined using congenic Dahl rats
Michael R. Garrett and John P Rapp
Hyperuricemia causes glomerular hypertrophy in the rat
Takahiko Nakagawaa, Marilda Mazzalia, Duk-Hee Kanga, John Kanellisa, Susumu Watanabea, Laura G. Sanchez-Lozadab, Bernardo Rodriguez-Iturbec, Jaime Herrera-Acostab, Richard J. Johnsona
Attenuation of the cardiovascular and metabolic complications of obesity in CD 14 knockout mice
Roncon-Albuquerque R Jr, Moreira-Rodrigues M, Faria B, Ferreira AP, Cerqueira C, Lourenco AP, Pestana M, von Hafe P, Leite-Moreira AF
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Buys ES, Sips P, Vermeersch P, Raher MJ, Rogge E, Ichinose F, Dewerchin M, Bloch KD, Janssens S, Brouckaert P
Non-invasive intraoperative monitoring of blood pressure and arterial pCO2 during surgical anesthesia in mice.
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Method for non-invasively
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Loss of SR-BI Expression Leads to the Early Onset of Occlusive Atherosclerotic
Coronary Artery Disease, Spontaneous Myocardial Infarctions, Severe Cardiac Dysfunction, and
Premature Death in Apolipoprotein E.Deficient Mice.
Braun A, Trigatti BL, Post MJ, Sato K, Simons M, Edelberg JM, Rosenberg RD, Schrenzel M,
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Electrocardiographic findings in mdx mice: a cardiac phenotype of Duchenne muscular
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Overexpression of Na+/Ca2+ exchanger gene attenuates postinfarction myocardial
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Probucol prevents early coronary heart
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Braun A, Zhang S, Miettinen HE, Ebrahim S, Holm TM, Vasile E, Post MJ, Yoerger DM, Picard MH, Krieger JL, Andrews NC, Simons M, Krieger M.
The Metabolic and Cardiovascular
Effects of Hyperthyroidism are Largely Independent of Beta-Adrenergic Stimulation.
Bachman E., Hampton TG, Dhillon H, Amende I,
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Invited review: Identifying new mouse models of
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Svenson KL, Bogue MA, Peters LL.
ECG Monitoring and Analyses
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Amende I, Dubach JM, Piskorski K, Morgan JP, and Hampton TG.
Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse
Kathryn E. Nichol, Anna I. Parachikova and Carl W. Cotman
Voluntary wheel running initially increases adrenal sensitivity to adrenocorticotrophic hormone, which is attenuated with long-term training.
Campbell JE, Rakhshani N, Fediuc S, Bruni S, Riddell MC
Cessation of daily wheel running differentially alters fat oxidation capacity in liver, muscle, and adipose tissue.
Laye MJ, Rector RS, Borengasser SJ, Naples SP, Uptergrove GM, Ibdah JA, Booth FW, Thyfault JP
The effects of chronic treadmill and wheel running on behavior in rats
Paul R. Burghardt, Laura J. Fulk, Gregory A. Hand and Marlene A. Wilson
Neurobiology of Mice Selected for High Voluntary Wheel-running Activity
Justin S. Rhodes, 
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Treadmill but not wheel running improves fatigue resistance of isolated extensor digitorum longus muscle in mice
J. A. L. Jeneson, M. W. de Snoo, N. A. T. Verlinden, B. J. L. J. Joosten, A. Doornenbal, A. Schot and M. E. Everts
Treadmill exercise, but not voluntary wheel running, facilitates aversive learning and memory
Hsiung-Ing Chen, Y.F Liu and C.J Jen
Treadmill exercise training fails to reverse defects in glucose, insulin and muscle GLUT4 content in the db/db mouse model of diabetes
Jacqueline Sennott, Joseph Morrissey, Paul R. Standley and Tom L. Broderick’
Anabolic steroid- and exercise-induced cardiac stress protein (HSP72) in the rat
W. Lunz, E.C. Oliveira, M.T.D. Neves, E.P.B. Fontes, C.M.G.C. Dias and A.J. Natali
Negative energy balance induced by voluntary wheel running inhibits polyp development in APCMin mice
Lisa H. Colbert, Volker Mai, Janet A. Tooze, Susan N. Perkins, David Berrigan and Stephen D. Hursting
The Effects of Aging and Treadmill Running on Soleus and Gastrocnemius Muscle Morphology in the Senescence-Accelerated Mouse (SAMP1)
Harutoshi Sakakima, Yoshihiro Yoshida, Shusaku Suzuki and Norio Morimoto
Synthesis of 2-substituted-6-(4H-1,2,4-triazol-4-yl)benzo[d]oxazoles as potential anticonvulsant agents
Wei CX, Guan LP, Jia JH, Chai KY, Quan ZS
Motor impairment and aberrant production of neurochemicals in human alpha-synuclein A30P+A53T transgenic mice with alpha-synuclein pathology
Tkeda M, Kawarabayashi T, Harigaya Y, Sasaki A, Yamada S, Matsubara E, Murakami T, Tanaka Y, Kurata T, Wuhua X, Ueda K, Kuribara H, Ikarashi Y, Nakazato Y, Okamoto K, Abe K, Shoji M
The effect of D1-like receptor blockade on motor functions and spatial learning in B6CBA mice
Voller J, Donek A, Cendeln J, Korelusova I, Vozeh F
A novel non-antibacterial, non-chelating hydroxypyrazoline derivative of minocycline inhibits nociception and oedema in mice
Bastos LF, Angusti A, Vilaca MC, Merlo LA, Nascimento EB Jr., Rocha LT, Godin AM, Solano AG, Jarussophon S, Nunan EA, Konishi Y, Coelho MM
IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination
Freude S, Leeser U, Muller M, Hettich MM, Udelhoven M, Schilbach K, Tobe K, Kadowaki T, Kohler C, Schroder H, Krone W, Bruning JC, Schubert M
Prevention of muscle fibrosis and improvement in muscle performance in the mdx mouse by halofuginone
Turgeman T, Hagai Y, Huebner K, Jassal DS, Anderson JE, Genin O, Nagler A, Halevy O, Pines M
Reinforcement of wheel running in BALB/c mice: role of motor activity and endogenous opioids
Vagas-Perex H, Sellings LH, Paredes RG, Proado-Alcala RA, Diaz JL
Comparison of two methods for measuring drug-induced neurotoxicity
R. Duane Sofia
Bodary PF, Shen Y, Ohman M, Bahrou KL, Vargas FB, Cudney SS, Wickenheiser KJ, Myers MG, Jr., and Eitzman DT. Leptin regulates neointima formation after arterial injury through mechanisms independent of blood pressure and the leptin receptor/STAT3 signaling pathways involved in energy balance. Arterioscler Thromb Vasc Biol 27: 70-76, 2007.
Day SM, Westfall MV, Fomicheva EV, Hoyer K, Yasuda S, La Cross NC, D'Alecy LG, Ingwall JS, and Metzger JM. Histidine button engineered into cardiac troponin I protects the ischemic and failing heart. Nat Med 12: 181-189, 2006.
Duan SZ, Ivashchenko CY, Whitesall SE, D'Alecy LG, Duquaine DC, Brosius FC, 3rd, Gonzalez FJ, Vinson C, Pierre MA, Milstone DS, and Mortensen RM. Hypotension, lipodystrophy, and insulin resistance in generalized PPARgamma-deficient mice rescued from embryonic lethality. J Clin Invest 117: 812-822, 2007.
Duan SZ, Ivashchenko CY, Whitesall SE, D'Alecy LG, and Mortensen RM. Direct monitoring pressure overload predicts cardiac hypertrophy in mice. Physiol Meas 28: 1329-1339, 2007.
Feng M, Whitesall S, Zhang Y, Beibel M, D'Alecy L, and DiPetrillo K. Validation of volume-pressure recording tail-cuff blood pressure measurements. Am J Hypertens 21: 1288-1291, 2008.
Fu Y, Huang X, Zhong H, Mortensen RM, D'Alecy LG, and Neubig RR. Endogenous RGS proteins and Galpha subtypes differentially control muscarinic and adenosine-mediated chronotropic effects. Circ Res 98: 659-666, 2006.
Huang X, Fu Y, Charbeneau RA, Saunders TL, Taylor DK, Hankenson KD, Russell MW, D'Alecy LG, and Neubig RR. Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 allele. Mol Cell Biol 26: 6870-6879, 2006.
Li J, McLerie M, and Lopatin AN. Transgenic upregulation of IK1 in the mouse heart leads to multiple abnormalities of cardiac excitability. Am J Physiol Heart Circ Physiol 287: H2790-2802, 2004.
Linder AE, Weber DS, Whitesall SE, D'Alecy LG, and Webb RC. Altered vascular reactivity in mice made hypertensive by nitric oxide synthase inhibition. J Cardiovasc Pharmacol 46: 438-444, 2005.
Park JL, Whitesall SE, D'Alecy LG, Shu L, and Shayman JA. Vascular dysfunction in the alpha-galactosidase A-knockout mouse is an endothelial cell-, plasma membrane-based defect. Clin Exp Pharmacol Physiol 35: 1156-1163, 2008.
Piao L, Li J, McLerie M, and Lopatin AN. Transgenic upregulation of IK1 in the mouse heart is proarrhythmic. Basic Res Cardiol 102: 416-428, 2007.
Whitesall SE, Hoff JB, Vollmer AP, and D'Alecy LG. Comparison of simultaneous measurement of mouse systolic arterial blood pressure by radiotelemetry and tail-cuff methods. Am J Physiol Heart Circ Physiol 286: H2408-2415, 2004
Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 allele.
Huang X, Fu Y, Charbeneau RA, Saunders TL, Taylor DK, Hankenson KD, Russell MW, D'Alecy LG, Neubig RR.
Ultrasound-guided left-ventricular catheterization: a novel method of whole mouse perfusion for microimaging
Zhou YQ, Davidson L, Henkelman RM, Nieman BJ, Foster FS, Yu LX, Chen XJ.
Proteasome inhibition promotes regression of left ventricular hypertrophy
Stansfield WE, Tang RH, Moss NC, Baldwin AS, Willis MS, Selzman CH
Mouse heart valve structure and function: echocardiographic and morphometric analyses from the fetus through the aged adult.
Robert B. Hinton, Jr., Christina M. Alfieri, Sandra A. Witt, Betty J. Glascock, Philip R. Khoury, D. Woodrow Benson, and Katherine E. Yutzey
Echocardiographic assessment of age-associated changes in systolic and diastolic function of the female F344 rat heart.
Boluyt MO. Converso K. Hwang HS. Mikkor A. Russell MW.
Rapamycin attenuates load-induced cardiac hypertrophy in mice.
Shioi T. McMullen JR. Tarnavski O. Converso K. Sherwood MC. Manning WJ. Izumo S.
Effect of cardioversion of atrial fibrillation on improvement in left ventricular performance.
Viswanathan K. Daniak SM. Salomone K. Kiely T. Patel U. Converso K. Manning WJ.
Single histidine button in cardiac troponin I sustains heart performance in response to severe hypercapnic respiratory acidosis in vivo.
Nathan J. Palpant, Louis G. D’Alecy, and Joseph M. Metzger
Initial experience with high frequency ultrasound for the newborn C57BL mouse.
Bose AK, Mathewson JW, Anderson BE, Andrews AM, Martin Gerdes A, Benjamin Perryman M, Grossfeld PD
Imaging kidney in conscious rats with high-frequency ult
Wang YX, Betton G, Floettmann E, Fantham E, Ridgwell G.
TitleImaging kidney in conscious rats with high-frequency ultrasound and detection of two cases of unilateral congenital hydronephrosis.
Wang, Yi-Xiang J. Betton, Graham. Floettmann, Eike. Fantham, Elizabeth. Ridgwell, Graham.
Uraemic hyperparathyroidism causes a reversible inflammatory process of aortic valve c
Shuvy M, Abedat S, Beeri R, Danenberg HD, PlanerC
Oncolytic Viral Therapy By Bladder Instillation Using An E1a, E1b Double-Restricted Adenovirus In An Orthotopic Bladder Cancer Model.
Hua Wang, Makoto Satoh, Hisashi Abe, Makoto SunamurU
Uterine vascular function in a transgenic preeclampsia rat model.
Verlohren S, Niehoff M, HGollasch M, Dechend R.
Pulse Wave Imaging in Murine Abdominal Aortas.
Kana Fujikura,Jianwen Luo, Mathieu Pernot, Royd Fukumoto*, DU
Ultrasound and Doppler micro-imaging in model of rheumatoid arthiritis in mice.
Gaëlle Clavel 1, Carmen Marchiol-Founigault 2, Gilles Renault 2, Ma
Non-invasive high-frequency vascular ultrasound elastography.
Maurice RL, Daronat M, Ohayon J, Stoyanova E, Foster FS, CloP
Increasing Peripheral Artery Intima Thickness From Childhood to Seniority.
Osika W, Dangardt F, Gronros J, Lundstam U, Myredal A, Johansson M, V
alpha2beta1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner.
Zhang Z, Ramirez NE, Yankeelov TE, Li Z, Ford LE, Qi Y, Pozzi A, Zutter MM
Ethier CR. Hemodynamics in the mouse aortic arch as assessed by MRI, ultrasound, and numerical modeling
Feintuch A. Ruengsakulrach P. Lin A. Zhang J. Zhou YQ. Bishop J. Davidson L. Courtman D. Foster FS. Steinman DA. Henkelman RM.
Cardiovascular Developmental Insights from Embryos.
Bradley B. Keller, LI J. Liu, Joseph P. Tinney and Kima
High resolution ultrasound-guided microinjection for interventional studies of early embryonic and placental development in vivo in mice
John C. Slevin, Lois Byers, Marina Gertsenstein, DB
Transitions in Early Embrby Tissue Composition
Jonathan T. Butcher, Tim C. McQuinn, David Sedmera, Debi TC
Uterine vascular function in a transgenic preeclampsia rat model.
Verlohren S, Niehoff M, HGollasch M, Dechend R.
Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer.
Derosier LC, Buchsbaum DJ, Oliver PG, Huang ZQC
Restricted Adenovirus In An Orthotopic Bladder Cancer Model.
Hua Wang, Makoto Satoh, Hisashi Abe, Makoto SunamurU
Ultrasonic detection and developmental changes in calcification of the placenta during normal pregnancy in mice.
Akirav C. Lu Y. Mu J. Qu DW. Zhou YQ. Slevin J. Holmyard D. Foster FS. Adamson SL.
Ovarian Volume Measurements in Mice With High-Resolution Ultrasonography.
Andrej Lyshchik, MD, PRonald R. Price, PhD
Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: the role of oxidative stress.
Dong LF, Swettenham E, Eliasson J, Wang XF, Gold M, Medunic Y, Stantic M, Low P, Prochazka L, Witting PK, Turanek J, Akporiaye ET, Ralph SJ, Neuzil J
Oncolytic viral therapy by bladder instillation using an E1A, E1B double-restricted adenovirus in an orthotopic bladder cancer model.
Wang H, Satoh M, Abe H, Sunamura M, Moriya T, Ishidoya S, Saito S, Hamada H, Arai Y
Therapeutic effect of CS-706, a specific cyclooxygenase-2 inhibitor, on gallbladder carcinoma in BK5.ErbB-2 mice.
Kiguchi K. Ruffino L. Kawamoto T. Franco E. Kurakata S. Fujiwara K. Hanai M. Rumi M. DiGiovanni J.
Experimental autoimmune prostatitis induces chronic pelvic pain
Rudick CN. Schaeffer AJ. Thumbikat P.
TitleMorphological differences between guinea pig aortic and venous endothelial cells in situ.
Katoh, Kazuo. Kano, Yumiko. Ookawara, Shigeo.
Embryonic and neonatal phenotyping of genetically engineered mice.
Kulandavelu, Shathiyah. Qu, Dawei. Sunn, Nana. Mu, Junwu. Rennie, Monique Y. Whiteley, Kathie J. Walls, Johnathon R. Bock, Nicholas A. Sun, John C H. Covelli, Andrea. Sled, John G. Adamson, S Lee.
Elimination of rutaecarpine and its metabolites in rat feces and urine measured by liquid chromatography
Woan-Ching Jan , Lie-Chwen Lin, Ming-Jaw Don, Chieh-Fu Chen, Tung-Hu Tsai
Uptake, Tissue Distribution, and Fate of Inhaled Carbon Tetrachloride: Comparison of Rat, Mouse, and Hamster
Benson J. M., Tibbetts B. M., Thrall K. D., Springer D. L.
The Metabolism of 14 C-Disulfiram by the Rat
Dewey H. Neiderhiser Ph.D., Richard K. Fuller M.D.
Resistance to diet-induced obesity and improved insulin sensitivity in mice with a regulator of G protein signaling-insensitive G184S Gnai2 allele.
Huang X, Charbeneau RA, Fu Y, Kaur K, Gerin I, MacDougald OA, Neubig RR.
Alcohol Consumption Promotes Body Weight Loss in Melanoma-Bearing Mice.
Nunnez, Nomeli P.; Carter, Patrick A.; Meadows, Gary G.
Calorigenic effect of diiodothyronines in the rat
A Lanni, M Moreno, A Lombardi and F Goglia
TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity
A. Bartolomuccia,b,c, G. La Corteb,d, R. Possentid,e, V. Locatellif, A. E. Rigamontig, A. Torsellof, E. Brescianif, I. Bulgarellif, R. Rizzie, F. Pavonea, F. R. D’Amatoa, C. Severinid, G. Mignognah, A. Giorgih, M. E. Schininàh, G. Eliai, C. Branciaj, G.-L. Ferrij, R. Contik, B. Cianik, T. Pascuccil, G. Dell’Omom, E. E. Mullerg, A. Levic, and A. Molesa
A high-fat, ketogenic diet induces a unique metabolic state in mice
Adam R. Kennedy,1 Pavlos Pissios,1 Hasan Otu,2 Bingzhong Xue,1 Kenji Asakura,1 Noburu Furukawa,1 Frank E. Marino,1 Fen-Fen Liu,1 Barbara B. Kahn,1 Towia A. Libermann,2 and Eleftheria Maratos-Flier1
Psychosocial stress affects energy balance in mice: Modulation by social status
A. Moles, A. Bartolomucci, L. Garbugino, R. Conti, A. Caprioli, R. Coccurello, R. Rizzi, B. Ciani and F.R. D'Amato
Inactivation of the Mouse Melanocortin-3 Receptor Results in Increased Fat Mass and Reduced Lean Body Mass
Airu S. Cen, Donald J. Marsh, Myrna Trumbauer, Easter G. Frazier, Xiao-Ming Guan, Hong Yu, Charles I. Rosenblum, Aurawan Vongs, Yue Feng, Linhai Cao, Joseph M. Metzger, Alison M. Strack, Ramon E. Camacho, Theodore N. Mellin, Christian N. Nunes, William Min, Jill Fisher, Shobhna Gopal-Truter, D. Euan MacIntyre, Howard Y. Chen and H.T. Van der Ploeg
Attenuation of Leptin Action and Regulation of Obesity by Protein Tyrosine Phosphatase 1B
Alan Cheng, Noriko Uetani, Paul D. Simoncic, Vikas P. Chaubey, Ailsa Lee-Loy, C. Jane McGlade, Brian P. Kennedy, and Michel L. Tremblay
Suppression of body fat accumulation in myostatin-deficient mice
Alexandra C. McPherron and Se-Jin Lee
Metabolic Adaptations of Three Inbred Strains of Mice (C57BL/6, DBA/2, and 129T2) in Response to a High-Fat Diet1
Alexandra Funkat, Christine M. Massa, Valentina Jovanovska, Joseph Proietto and Sofianos Andrikopoulos2
Dynorphin Knockout Reduces Fat Mass and Increases Weight Loss during Fasting in Mice
Amanda Sainsbury, Shu Lin, Keely McNamara, Katy Slack, Ronaldo Enriquez, Nicola J. Lee, Dana Boey, George A. Smythe, Christoph Schwarzer, Paul Baldock, Tim Karl, En-Ju D. Lin, Michelle Couzens and Herbert Herzog
Diaspirin Crosslinked Hemoglobin Improves Systemic Oxygen Uptake in Oxygen Supply-dependent Septic Rats
Andreas W. Sielenkamper, Ian H. Chin-Yee, Claudio M. Martin, and William J. Sibbald
The metabolic profile of early Huntington's disease- a combined human and transgenic mouse study
Anna O.G. Goodman, Peter. R. Murgatroyd, Gema Medina-Gomez, Nigel I. Wood, Nicholas Finer, Antonio J. Vidal-Puig, A. Jennifer Morton and Roger A. Barker